Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules Using Minimum Additives
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چکیده
منابع مشابه
Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives
Atorvastatin calcium, a lipid-lowering drug, is much less bioavailable because of reduced solubility in acidic media. Multiple-unit floating microcapsules of Atorvastatin calcium (ATC) were developed to expand the gastric residence time of the drug, as ATC has maximum rate of absorption in the upper GI tract. Floating microcapsules were prepared by Emulsion-solvent evaporation technique through...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2012
ISSN: 0036-8709,2218-0532
DOI: 10.3797/scipharm.1104-26